Day #323 - Autoimmune Hepatitis

See approach to massive transaminitis here.

There is a nice NEJM review on autoimmune hepatitis here. The table below is linked from there.

Labs:

• In general, ANA is positive more than 1:80, anti-smooth muscle antibody 1:80, there is an elevated IgG, pANCA may be positive

Treatment:

• Prednisone 20-60mg per day with AZATHIOPRINE 50-100mg per day
• Maintentance with AZATHIOPRINE (or other)
• Goal is normalization of liver enzymes and IgG.