Friday, July 4, 2008

Management of DKA

Thank you to those who participated in our small group discussion on management of DKA. This was a first attempt at running such a session, so hopefully the next one will be even more effective.

The takeaway points (as I see them are):
* Stabilize the patient first while doing everything else
  • large bore IVs with NS for hypovolemia
  • foley as required
  • think about arterial line in the sicker patients
* History/Px/Labs to look for volume status and precipitant
* Insulin:
  • When you know the K+ isn't very low start the insulin
  • 0.1u/kg bolus then rate 0.1u/hr titrated to IV sliding scale
  • If glucose not falling can increase the dose, but be sure they are volume replete
  • Add dextrose (D5W or 2/3-1/3) when glucose <~13
  • Continue until patient has normal glucose and no anion gap and is ready to eat
* Potassium
  • Add K+ to the IV as soon as they are urinating and K+ <5
  • Oral repletion for hypokalemia in addition to IV.
  • Hold insulin when K+ <3.3
* Sodium/Water Balance
  • Use IV NS until you have reversed the signs of shock
  • Then change to a hypotonic fluid like 1/2NS or 2/3-1/3 or D5W
* Treat the precipitant

As promised, here is my favorite article on the management of DKA/HONK.

This is my favorite figure from the article if you don't want to read it all:

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