Today we heard a case of auto-immune haemolytic anemia presenting as symptomatic anemia. The patient may have had a prodromal illness.
This is a great article on AIHA. This one is good too.
In reading these something interesting became clear -- in what appears to be AIHA with a negative DAT there are a few possibilities.
- Subthreshold antibody (below the level of detection with DAT) -- this may be mitigated using a different method of DAT
- hereditary spherocytosis
- clostridial sepsis
- Two interesting ones include wilson's disease and Zieve's syndrome.
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